IAHS is a rare clinicopathologic entity characterized by fever, pancytopenia, liver dysfunction and the reactive proliferation of histiocytes actively phagocytosing hemopoietic cells, simulating the malignant histiocytosis, but distinct in that
the
phagocytosing histiocytes are morphologically mature and benign.
This syndrome occurs in patients who develop infections in the setting of preexisting immunological abnormalities or neoplasm, and usually runs a self-limited course, although in a minority of cases fatal outcomes ensue.
Recently, the author experienced a case of IAHS developed during immunosuppressive therapy in uveitis patient.
So we report this case with brief review of literatures.
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